Vagus Nerve Stimulation for Stress Relief

Jenna Hilton
August 6, 2025

The nervous system, which consists of a wide network of nerves extending through our body and relaying information from different organs and tissues, is responsible for regulating our emotions. Automatic, involuntary actions of these nerves mediate much of what we feel and experience. One of the largest and most important nerves in our body is the vagus nerve.

This article details all we should know about the vagus nerve. Though it regulates involuntary activities, we can make certain changes in life to engage the vagus nerve and improve its function.

Vagus nerve stimulation

What Is the Vagus Nerve?

The vagus nerve, also known as cranial nerve X, is the primary nerve in the parasympathetic nervous system – a branch of the autonomic nervous system responsible for “rest and digest” functions. These include heart rate, respiratory rate, digestion, and certain reflex actions like coughing and swallowing. The vagus nerve works in balance with the sympathetic nervous system, which governs the “fight or flight” response.

The vagus nerve is composed of sensory and motor fibers. The sensory neurons transmit information from different organs, such as the lungs, heart, gastrointestinal tract, to the brain via vagal pathways. The motor neurons control various muscles in the pharynx, larynx, and soft palate, and contribute to autonomic regulation of visceral organs through parasympathetic fibers.

Vagus Nerve Anatomy

The vagus nerve is the longest cranial nerve in the body, extending from the medulla oblongata (the lowest part of the brainstem) through the neck, chest, and into the abdomen. It connects the brain to various organs, including the heart, lungs, and digestive tract.

The vagus nerve consists of two main branches, the left and the right vagus nerves, which travel down either side of the body. In the chest, they form an esophageal plexus around the esophagus and enter the abdomen as the anterior and posterior vagal trunks.

Vagal nerves receive sensory input from and provide motor and parasympathetic output to the following areas:

  • Head – Small areas behind the ears and part of the external auditory canal.
  • Neck – Pharynx (throat) and larynx (voice box).
  • Chest – Heart and lungs.
  • Abdomen – Stomach, liver, pancreas.
  • Intestines – Small intestine and first part of the large intestine.

Vagus Nerve Branches

Vagal nerves extend into multiple branches that innervate the organs from the head to the abdomen, including the following:

  • Auricular branch – Innervates part of the external ear.
  • Pharyngeal branch – Innervates the throat (pharynx) and is involved in swallowing and speech.
  • Laryngeal branches – Innervate the voice box (larynx) and are involved in speaking and breathing.
  • Cardiac branches – Help to slow down the heart rate and contribute to relaxation.
  • Bronchial branches – Innervate the lungs and help regulate breathing.
  • Esophageal branches – Control the muscles of the esophagus to support swallowing.
  • Gastric and celiac branches – Innervate the stomach, pancreas, kidneys, adrenals, and the small intestine to help regulate digestion.

What Is the Function of the Vagus Nerve?

The vagus nerve controls involuntary sensory and motor activities, mediating the following functions:

  • Taste sensation
  • Saliva production
  • Swallowing
  • Digestion
  • Speech
  • Breathing
  • Heart rate
  • Immune response
  • Mood

One of the vagus nerve’s primary functions is to help the body calm and rest physical or emotional stress. It transmits signals from the brain to the rest of the body, letting the body know that the danger or physical/emotional stress has passed.

By activating the parasympathetic nervous system, the vagus nerve helps counteract the effects of the sympathetic nervous system, which is responsible for the “fight or flight” response, including increased heart rate and heightened stress.


Note: To learn more about the subject, read our blog post on stress and hormones to learn how the endocrine system is involved in our mental health.


What Is Vagus Nerve Stimulation?

Vagus nerve stimulation (VNS) is a medical procedure that involves sending electrical impulses to the left vagus nerve to modulate brain activity and improve vagus nerve disorders. There are two types of VNS devices:

  1. Surgically implanted VNS devices under the patient’s skin in the chest, with electrical wires connecting to the left vagus nerve in the neck. The device delivers electrical pulses to stimulate the nerve.
  2. Non-invasive VNS devices externally placed on the skin of the outer ear or neck, sending electrical impulses to the auricular branch of the vagus nerve (in the ear).

Vagus nerve stimulation is designed to improve conditions related to vagus nerve disorders. Currently, it is approved for epilepsy, treatment-resistant depression, stroke rehabilitation, and cluster headaches. Scientists are exploring its potential for treating rheumatoid arthritis, inflammatory bowel disease, Alzheimer’s, obesity, and other conditions.

Vagus Nerve Stimulation for Stress Relief

Exercise for vagus nerve stimulation

Vagus nerve stimulation shows promise in the treatment of stress-related psychiatric disorders, particularly post-traumatic stress disorder (PTSD) and severe depression. Studies show it may modulate the patient’s autonomic response and enhance recovery from acute traumatic stress.

Health experts also recognize a potential for relieving emotional stress through lifestyle practices that strengthen the vagus nerve, such as regular exercise, healthy sleep, and meditation.

Other Benefits of Vagus Nerve Stimulation

Besides stress relief, researchers have found the following beneficial effects of vagus nerve stimulation:

  • Enhanced memory and cognition, which can help with neurodegenerative disorders.
  • Improved norepinephrine function, which contributes to VNS’s antidepressant effects.
  • Reduced inflammatory response, which may help manage arthritis, IBD, and obesity.

Risks of Vagus Nerve Stimulation

Surgical vagus nerve stimulation can cause certain side effects. These include:

  • Infection
  • Pain at the incision site
  • Trouble swallowing
  • Temporary paralysis of the vocal cords
  • Shortness of breath
  • Headaches

Non-invasive VNS comes with fewer and less severe side effects, such as skin irritation, headaches, and voice changes.

Natural vagus nerve stimulation through lifestyle changes is safe and can only improve overall health.

Who Should Try Vagus Nerve Stimulation?

Medical vagus nerve stimulation can help patients with certain chronic conditions that don’t respond to traditional treatments, such as medications and psychotherapy. The conditions include drug-resistant epilepsy, treatment-resistant depression, and cluster headaches.

The treatment can also help stroke patients to regain their arm motor function and cognitive skills. Surgical and non-invasive VNS treatments require consultation with a healthcare provider.

People dealing with stress-related health issues, such as anxiety and burnout, may benefit from natural vagus nerve stimulation through healthier lifestyle practices and relaxing activities.

Who Should Avoid Vagus Nerve Stimulation?

Certain medical reasons, interventions, and other conditions may prevent you from receiving VNS. These include the following:

  • Baseline cardiac conduction disorders, which affect the speed and regularity of the heartbeat (e.g., arrhythmias).
  • Prior bilateral or left cervical vagotomy (surgical removal of vagus nerve branches).
  • Having one vagus nerve.
  • An implanted device, such as a pacemaker.
  • Lung or breathing disorders, including asthma and sleep apnea.
  • Active peptic ulcers.
  • Certain psychiatric disorders, such as schizophrenia and rapid cycling bipolar disorder.
  • Pregnancy.

Consult your healthcare provider to determine your eligibility for this medical procedure.

Many natural vagus nerve stimulation methods are suitable for everyone, including meditation and a healthier diet.

How to Stimulate the Vagus Nerve?

A healthy vagus nerve can positively impact various health parameters. These natural strategies for toning and strengthening the vagus nerve may improve stress response, reduce anxiety, lower inflammation, and enhance mental health.

Healthy Nutrition

The state of our gut significantly impacts the vagus nerve and the signals it sends from the gastrointestinal tract to the brain. A healthy gut promotes a healthy gut-brain connection and supports optimal vagal function.

Foods that help beneficial gut microorganisms thrive are rich in fiber, probiotics, prebiotics, omega-3 fatty acids, polyphenols, and antioxidants. They include fruits and vegetables, lean protein, whole grains, nuts, and seeds. Anti-inflammatory diets like the Mediterranean diet have consistently shown benefits to gut and nervous system health.

Regular Exercise

Exercise provides more oxygen and energy to the body, which activates the vagus nerve. Regular physical activity helps strengthen it. Some of the best exercises for vagus nerve stimulation include interval and endurance training, tai chi, and yoga.

Deep Breathing

Deep breathing involves inhaling slowly and deeply through the nose and exhaling through the mouth. The goal is to extend the exhalations, making them longer than the inhalations. This helps maximize oxygen intake, slow the heart rate, lower cortisol levels, and promote relaxation.

Singing and Humming

Singing and humming create vibrations in the throat and chest that stimulate branches of the vagus nerve involved in vocalization and breathing. These activities help activate the parasympathetic nervous system, promoting a sense of calm.

Meditation

Meditation is a mindfulness practice that involves various relaxation techniques, including deep breathing, singing, humming, chanting, heightened awareness of the present moment, and other practices that stimulate the vagus nerve.

Massage

Massage stimulates and relaxes muscles and nerves in the skin. Gently massaging the neck, area behind the ear, and shoulders may activate the vagus nerve, help reduce stress, and improve mood.

Cold Water Therapy

Immersing the body in cold water (50-60°F) for up to 15 minutes may provide certain health benefits, such as improved blood circulation, mood, and immune function. By working to restore its core temperature, the body slows down heart rate and breathing, engaging the vagus nerve and promoting relaxation.

Cold water therapy includes cold water immersion, cold baths, cold showers, etc.

Conclusion

The vagus nerve is one of the largest nerves, connecting the brain with the rest of the body down to the abdomen. It is the primary nerve of the parasympathetic nervous system, which regulates our stress response. Adopting healthier lifestyle practices is the best way to engage and strengthen the vagus nerve. This will help the body adapt to stressful events more easily and improve our overall health.

Jenna Hilton
Jenna Hilton has been a practicing PA since 2009, specializing in Family, Internal Medicine and Medical Aesthetics. She attended Arizona State University where she received her Bachelor's Degree and graduated magna cum laude. She received her Master of Science degree in Physician Assistant Studies from A.T. Still University.

Jenna has been injecting neurotoxin and dermal filler since 2013. She received certification as a Master Injector in 2017 through Empire Medical in Los Angeles, California. She is currently working on a Fellowship Program in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. Her special interests include use of PLLA, Ablative/Non ablative skin resurfacing, PDO threads, hormone therapy and nutritional therapies to improve cellular regeneration and medically supervised weight loss.

Jenna Hilton believes in a multi-factorial approach, considering internal factors that accelerate aging and disease development. She always enjoys teaching. She co-founded Vibrant EDU courses at Vibrant Skin Bar and regularly performs one-on-one training with fellow injectors. She teaches Aesthetic and Advanced Injectable Courses at National Laser Institute. She has been named Preceptor of the Year and is an Adjunct Faculty Member at Midwestern University. She was born in Iowa, and lives with her husband and three children in Phoenix, AZ.

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