Can Low Testosterone Cause Fatigue?

Jenna Hilton
December 7, 2023

Low testosterone affects both men and women, usually due to aging or medical reasons. The hormone regulates many bodily functions, and its decline can lead to unpleasant symptoms. One of the most common is fatigue – extreme and chronic tiredness that impairs the patient’s quality of life.

This article explains how low testosterone causes fatigue and what to do.

Low testosterone and fatigue

Can Low Testosterone Cause Fatigue?

Fatigue is one of the most common symptoms of low testosterone. It is more severe than common tiredness that can be restored after a good night’s rest and often results from a lack of energy due to mental and emotional strain.

Scientists don’t fully understand the link between testosterone and energy levels, but studies show the hormone affects cognitive functions, mood, sexual function, and muscle mass. When these functions are out of balance, they lead to a lack of energy, low mood, and fatigue.

Note: Does testosterone give you energy? Read our article and find out.

What Does Testosterone Fatigue Feel Like?

People with testosterone fatigue usually experience extreme exhaustion and no motivation for basic daily activities, including going to work, socializing, and sexual life. Fatigue is a debilitating symptom that doesn’t improve after sleep or rest. Unfortunately, it perpetuates other low testosterone symptoms, including weight gain, loss of muscle mass, and depression.

Other Symptoms of Low Testosterone

Low testosterone may cause the following symptoms:

Note: Learn more about the correlation between sleep and testosterone, or read about how chronically low testosterone levels can contribute to hormonal depression.

How to Fight Fatigue Caused by Low Testosterone

Testosterone replacement therapy (TRT) is the most effective way to relieve symptoms of low testosterone. Recent studies show long-term TRT can significantly reduce fatigue scores.

The therapy involves replacing testosterone using approved medication. TRT comes in the form of creams, pellets, injections, and skin patches.

Other ways to fight low testosterone fatigue include:

  • Regular exerciseResearch suggests increased physical activity naturally enhances testosterone levels, especially high-intensity interval training and strength training with weights. Incorporate at least two weekly workouts and 30 minutes of moderate physical activity (e.g., brisk walking) daily.
  • Energy-boosting supplements – Fatigue usually makes it difficult to find motivation to exercise, but dietary supplements that enhance energy levels can help. Consult your medical provider about the best product to use.
  • Balanced diet – We need vitamins, minerals, and other nutrients for our cells to properly function and create energy. A diet that boosts health and optimal energy levels includes fruits, vegetables, lean protein, and healthy fats. Sugary, processed foods, and alcohol can worsen a hormonal imbalance.  
  • Healthy sleep – The body needs rest and sleep to renew and repair itself. Aim for at least seven hours of uninterrupted sleep at night to prevent low testosterone fatigue.

Note: Learn how TRT can support weight loss.


Fatigue often results from declining testosterone. Learn to recognize the symptoms of low testosterone and implement lifestyle changes and treatments that will improve your daily life and well-being.

If you’re looking for testosterone replacement therapy in Phoenix, let our experienced medical professionals help you!

Jenna Hilton
Jenna Hilton has been a practicing PA since 2009, specializing in Family, Internal Medicine and Medical Aesthetics. She attended Arizona State University where she received her Bachelor's Degree and graduated magna cum laude. She received her Master of Science degree in Physician Assistant Studies from A.T. Still University.

Jenna has been injecting neurotoxin and dermal filler since 2013. She received certification as a Master Injector in 2017 through Empire Medical in Los Angeles, California. She is currently working on a Fellowship Program in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. Her special interests include use of PLLA, Ablative/Non ablative skin resurfacing, PDO threads, hormone therapy and nutritional therapies to improve cellular regeneration and medically supervised weight loss.

Jenna Hilton believes in a multi-factorial approach, considering internal factors that accelerate aging and disease development. She always enjoys teaching. She co-founded Vibrant EDU courses at Vibrant Skin Bar and regularly performs one-on-one training with fellow injectors. She teaches Aesthetic and Advanced Injectable Courses at National Laser Institute. She has been named Preceptor of the Year and is an Adjunct Faculty Member at Midwestern University. She was born in Iowa, and lives with her husband and three children in Phoenix, AZ.

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