Vitamin D IV: Uses and Benefits

Jenna Hilton
June 8, 2023

Vitamin D plays a crucial role in numerous physiological processes, including bone health, immune function, and regulation of cellular growth and development. This is why it is essential to maintain optimal vitamin D levels in the body.

Vitamin D is primarily obtained through sunlight exposure and food, but some people experience deficiencies or difficulties absorbing vitamin D. In these cases, vitamin D intravenous (IV) therapy is a smart solution for replenishing depleted levels in the body.

In this article, learn about vitamin D IV therapy, its uses and benefits for your health.

what is vitamin d iv therapy

What Is Vitamin D IV Therapy?

Vitamin D IV therapy is an intravenous treatment containing vitamin D and other vitamins and minerals prescribed by your medical provider on the basis of your symptoms.

IV therapy is an effective way to administer vitamins directly into your bloodstream and bypass the digestive system. This allows for immediate absorption and utilization in the body and immediate improvement of vitamin D levels.

Vitamin D Deficiency: Causes and Symptoms

Many factors can cause vitamin D deficiency:

  • Little to no sun exposure
  • Excessive use of sunscreen
  • Poor diet
  • Obesity
  • Darker complexion
  • Kidney or liver disease
  • Certain types of cancer (lymphoma)

The symptoms of vitamin D deficiency include:

  • Weight gain
  • Low energy
  • Hair loss
  • Muscle pain
  • Bad mood
  • Fatigue
  • Difficulty sleeping

Vitamin D IV Therapy Benefits

Vitamin D IV therapy increases levels of this essential vitamin, positively impacting the following processes and conditions in the body.

Stronger and Healthier Bones

Without vitamin D, the body is not able to store and utilize calcium, which can lead to issues such as bone weakness, skeletal deformities, and posture problems.

During menopause, drops in estrogen levels cause loss of bone mass and bone density, which can result in osteoporosis. Vitamin D deficiency can exacerbate osteoporosis, so having sufficient levels of this vitamin helps maintain bone mineral density.

Note: The hormonal shifts that occur during perimenopause and menopause can bring on many uncomfortable symptoms. The experts at Vibrant Vitality Clinic have years of experience administering female hormone replacement therapy in the Phoenix area so you can bring back enjoyment to your everyday life.

Improved Immune System

Vitamin D plays a crucial role in building the immune system and regulating the body’s immune responses. It protects the body from foreign pathogens by attaching itself to immune cell receptors and encouraging them to create protective antimicrobial peptides.

Vitamin D also helps to reduce inflammation as it lowers the levels of cytokines, shifting the body from an inflammatory response. For this reason, it is essential in preventing and curing chronic inflammation, which leads to many serious illnesses.

Note: Learn more about the best vitamins for an immune system boost.

Controlled Cellular Growth and Differentiation

Vitamin D contributes to healthy and controlled cell growth. When cells proliferate, they can mutate and lead to cancer. Vitamin D prevents this from happening by improving cell differentiation – the process that controls cell growth and tells in which process to specialize.

Although Vitamin D’s anticancer properties have not been fully established, research shows that optimal doses of this vitamin do reduce cancer mortality rates.

Better Circulation and Heart Health

Vitamin D improves circulation by protecting the lining of the blood vessels and arteries, keeping them relaxed. It also reduces levels of angiotensin, the hormone which contributes to high blood pressure.

Scientific evidence shows that low levels of vitamin D increase the risk of high blood pressure and cardiovascular disease.

Effective Digestion

Levels of active vitamin D in the gut have been linked to microbiome diversity and the number of “friendly” bacteria in the intestine.

Gut health is essential for not only maintaining a robust immune system, it also helps keep inflammation in check. Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, have been linked to a disturbed microbiome and dysregulation of the immune response. One way to keep our gut happy is to have sufficient levels of vitamin D in our system.

Improved Mental Health

Vitamin D alleviates symptoms of depression and improves mood by increasing the availability of serotonin in the brain. The vitamin also has a role in melatonin regulation, positively affecting sleep patterns.

In contrast, vitamin D deficiency can lead to mood swings, trouble sleeping, lack of concentration, and depressive episodes.

Note: Hormonal changes can affect the quality of sleep and cause insomnia. Read more about hormonal insomnia on our blog.

Better Reproductive Health

Fertility problems, especially polycystic ovary syndrome (PCOS), have been linked to vitamin D deficiencies. In fact, the severity of PCOS is correlated with the degree of vitamin D deficiency.

Research has shown that vitamin D plays a role in egg development, increasing the chances of conception. Furthermore, optimal levels reduce the risk of maternal and fetal complications.

Efficient Weight Loss

Studies have shown that people on a weight loss program who were also taking vitamin D supplements experienced more significant weight loss and had less belly fat than people taking a placebo.

Scientists hypothesize that vitamin D helps weight loss by decreasing the formation of fat cells and reducing their storage in the body. It also increases the levels of serotonin, the neurotransmitter that helps control appetite and reduce calorie intake.

Note: Learn about the benefits of IV therapy for weight loss.

Diabetic Support

Studies show that vitamin D may improve insulin resistance by reducing inflammation in the body. Combined with calcium intake, vitamin D also promotes insulin secretion, which improves patients’ glycemic status.

Note: Learn more about the relationship between insulin resistance and weight loss.

Vitamin D Deficiency Treatment

Vitamin D IV therapy helps successfully treat vitamin D deficiency as it assists the body in reaching and maintaining optimal levels of the vitamin. Treatment is best combined with the intake of vitamin D-rich food, such as fish, egg yolk, and beef liver.

Depending on the severity of the symptoms, your medical provider could also recommend a combination of oral supplements or vitamin D injections.

How Does Vitamin D IV Therapy Work?

how does vitamin d iv therapy work

Vitamin D IV therapy begins with a medical provider gently inserting an IV line into the vein in your arm to connect you to the IV bag. The IV bag contains a mix of vitamin D and other vitamins and minerals that help your body absorb the nutrients faster and more efficiently.

The IV drip slowly delivers vitamin D into your bloodstream, bypassing your digestive organs and allowing the body to reach higher levels quickly.

Vitamin D IV therapy typically lasts from 20 minutes to one hour, depending on your medical provider’s recommendation on the amount of fluid you should receive.

The number of treatments is recommended to each patient individually. Their frequency can vary from two or three times a week for treating specific illnesses and deficiencies to every two weeks or once a month for promoting overall health and wellness.

Note: Learn more about different types of IV fluids.

What to Expect from Vitamin D IV Therapy?

The effects of vitamin D IV therapy kick in right away. Patients experience higher energy levels and improved mental clarity as early as the same day of the treatment.

After the treatment, some patients might experience slight pain at the injection site and bruising or swelling. If this happens, patients can put an ice pack on the injected area and resume all activities while ensuring not to injure the injected arm.

The treatment itself may cause side effects similar to feeling jet-lagged or hungover, which is common for all IV therapy treatments and does not last very long.

How Much Does Vitamin D IV Therapy Cost?

The cost of vitamin D IV therapy depends on the number of treatments and the amount of fluid your medical provider recommends. Typically, IV therapy costs between $100 and $300.

Who Is a Good Candidate for Vitamin D IV Therapy?

Almost anyone who wishes to receive a vitamin D boost can get it through IV therapy. It is equally beneficial for patients with health issues stemming from vitamin D deficiency and people who just want to raise their energy and improve their mood.

However, vitamin D IV therapy is not recommended for the following groups:

  • People with sufficient levels of vitamin D
  • Pregnant women
  • People with kidney disease
  • Women who are breastfeeding
  • People with high blood pressure
  • People with heart conditions
  • People who are currently taking certain medications (such as medication for stimulating red blood cell production, bacterial or virus infection medication)


Vitamin D IV therapy is a promising approach to resolving vitamin D deficiencies and improving overall health. Vitamin D contributes to bone health, a strong immune system, and mood regulation. It also reduces the risk of chronic disease, heart conditions, and some forms of cancer.

For nutritional IV therapy in Phoenix, come to Vibrant Vitality Clinic to find the appropriate treatment plan, dosage, and frequency of vitamin D IV therapy.

Jenna Hilton
Jenna Hilton has been a practicing PA since 2009, specializing in Family, Internal Medicine and Medical Aesthetics. She attended Arizona State University where she received her Bachelor's Degree and graduated magna cum laude. She received her Master of Science degree in Physician Assistant Studies from A.T. Still University.

Jenna has been injecting neurotoxin and dermal filler since 2013. She received certification as a Master Injector in 2017 through Empire Medical in Los Angeles, California. She is currently working on a Fellowship Program in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine. Her special interests include use of PLLA, Ablative/Non ablative skin resurfacing, PDO threads, hormone therapy and nutritional therapies to improve cellular regeneration and medically supervised weight loss.

Jenna Hilton believes in a multi-factorial approach, considering internal factors that accelerate aging and disease development. She always enjoys teaching. She co-founded Vibrant EDU courses at Vibrant Skin Bar and regularly performs one-on-one training with fellow injectors. She teaches Aesthetic and Advanced Injectable Courses at National Laser Institute. She has been named Preceptor of the Year and is an Adjunct Faculty Member at Midwestern University. She was born in Iowa, and lives with her husband and three children in Phoenix, AZ.

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